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[NeoBioPharma] GCaMP3-Expressing Human Umbilical Vein Endothelial Cells

Cat-No. NBP-0001-GCaMP3


NeoBiopharma는 혁신적인 소분자 신약 설계와 구조 최적화 기술을 기반으로 차세대 치료제를 개발하는 바이오테크 기업입니다.





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GCaMP3-Expressing Human Umbilical Vein Endothelial Cells




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NBP-0001-GCaMP3



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Product TypeHuman Endothelial cells
Viability>98% viable (Trypan Blue exclusion)
StorageStore in liquid nitrogen vapor phase (-196°C) for long-term. Ship on dry ice (-80°C).
Shelf LifeVery stable in the Liquid Nitrogen Vapor Phase



Description

GCaMP3-Expressing Human Umbilical Vein Endothelial Cells (HUVECs) represent a significant advancement in the visualization and measurement of calcium signaling within endothelial cells.

These specialized cells allow researchers to observe dynamic changes in calcium levels, which are critical for various cellular functions. By employing GCaMP3, a genetically encoded calcium indicator, scientists can gain deeper insights into the intricate processes that govern endothelial physiology and its alterations during disease states.

Additionally, these cells are invaluable in the realm of drug discovery and mechanistic investigations, providing a platform for exploring treatments related to vascular health and disorders. This technology ultimately fosters a more comprehensive understanding of the roles endothelial cells play in both physiological and pathological contexts.

GCaMP3-expressing HUVECs provide a powerful tool for visualizing and quantifying calcium signaling in endothelial cells. Their use facilitates a better understanding of endothelial physiology and pathophysiology, and they are instrumental in drug discovery and mechanistic studies related to vascular health and disease.

Guarantee expansion for a minimum of 2-5 population doublings.

IMPORTANT: Quality warranty requires use of NeoBioPharma media. Biohazardous material despite negative pathogen testing. Quality claims must be reported within 1 month.

Key Features

Catalog Number: NBP-0001-GCaMP3
Product Format: Frozen
Vial Cell Number: > 5x10[5] cells/vial
Passage:1(P1)
Storage: Liquid Nitrogen, Vapor Phase
Intended Use: Research use only (RUO)

CELLS CHARACTERIZATION

GCaMP3-expressing human umbilical vein endothelial cells (HUVECs) are genetically engineered endothelial cells that have been modified to express GCaMP3, a genetically encoded calcium indicator.

This allows for the real-time monitoring of intracellular calcium dynamics in living cells. These cells retain typical endothelial properties, including cobblestone morphology, expression of endothelial markers (such as CD31 and VE-cadherin), and the ability to form tubular networks.



Technical Specifications

Product Type
Human Endothelial cells
Viability
>98% viable (Trypan Blue exclusion)
Proliferative Capability
Primary cells capable of multiple passages when using recommended medium and proper handling
Storage Conditions
Store in liquid nitrogen vapor phase (-196°C) for long-term. Ship on dry ice (-80°C).
Shelf Life
Very stable in the Liquid Nitrogen Vapor Phase
Product Code
NBP-0001-GCaMP3
Size/Format
1ml
Primary Applications
GCaMP3-expressing HUVECs are widely used in vascular biology and cell signaling research to study calcium signaling pathways. They enable high-resolutionnon-invasive imaging of calcium flux in response to various stimulimaking them valuable for investigating endothelial functionmechanotransductionangiogenesisand the effects of pharmacological agents on vascular cells.





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