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제품 설명 

Daratumumab Biosimilar – Anti-CD38 mAb – Research Grade

제품 번호

PX-TA1213

제품 특징

Description of Daratumumab Biosimilar - Anti-CD38 mAb - Research Grade

General information on Anti-CD38(Homo sapiens) (Daratumumab) Monoclonal Antibody

Daratumumab is an immunoglobulin G1 kappa monoclonal antibody against CD38+ multiple myeloma cells.

QC & Validation Data

SDS-PAGE for Daratumumab Biosimilar - Anti-CD38 mAb

Daratumumab Biosimilar - Anti-CD38 mAb, on SDS-PAGE under reducing and non-reducing conditions. The gel was stained overnight with Coomassie Blue. The purity of the antibody is greater than 95%.

Daratumumab Biosimilar - Anti-CD38 mAb binds to CD38 Recombinant Protein in indirect ELISA Assay

Immobilized CD38 Recombinant Protein (cat. No.PX-P4081) at 0.5µg/mL (100µL/well) can bind to Daratumumab Biosimilar - Anti-CD38 mAb (cat. No.PX-TA1213) in indirect ELISA with Goat Anti-Human IgG secondary antibody coupled with HRP measured by OD450

Publications

• Rebecca J. Brownlie, Ruth Kennedy, Erica B. Wilson, Maja Milanovic, Claire F. Taylor, Dapeng Wang, John R. Davies, Heather Owston, Emma J. Adams, Sophie Stephenson, Rebecca Caeser, Benjamin E. Gewurz, Peter V. Giannoudis, Claudio Scuoppo, Dennis McGonagle, Daniel J. Hodson, Reuben M. Tooze, Gina M. Doody, Gordon Cook, David R. Westhead, Ulf Klein; Cytokine receptor IL27RA is an NF-κB–responsive gene involved in CD38 upregulation in multiple myeloma. Blood Adv 2023; 7 (15): 3874–3890. doi: https://doi.org/10.1182/bloodadvances.2022009044

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