Proteogenix는 Primary Antibody Biosimilar - Research Grade
제품을 전문적으로 생산하는 20년의 경험이 있는 High Quality 제조사입니다.
제품 설명
제품 번호
PX-TA1058
제품 특징
| Product name | Pertuzumab Biosimilar - Anti-ERBB2, EGFR2, CD340 mAb - Research Grade |
|---|---|
| Source | CAS 380610-27-5 |
| Species | Humanized |
| Expression system | Mammalian cells |
| Purity | >85% |
| Buffer | PBS buffer PH7.5 |
| Delivery condition | Blue ice (+4°C) |
| Delivery lead time in business days | 3-5 days if in stock; 3-5 weeks if production needed |
| Delivery Time | 3-5 days if in stock; 3-5 weeks if production needed |
| Storage condition | store at -80°C |
| Brand | ProteoGenix |
| Aliases /Synonyms | Pertuzumab,OMNITARG,rhuMAB 2C4,ERBB2, EGFR2, CD340,anti-ERBB2, EGFR2, CD340 |
| Reference | PX-TA1058 |
| Note | For research use only. Not suitable for human use. |
| Isotype | IgG1-kappa |
| Clonality | Monoclonal Antibody |
Pertuzumab is a recombinant humanized monoclonal antibody that targets the extracellular dimerization domain (subdomain II) of human epidermal growth factor receptor 2 protein (HER2). It was first used with docetaxel and another HER2-targeting monoclonal antibody trastuzumab to treat metastatic HER2-positive breast cancer. Since then, its indications have been expanded to be used as both neoadjuvant therapy and adjuvant therapy for the treatment of HER2-positive breast cancer with a high risk of recurrence.
QC & Validation Data
Immobilized CD340 Recombinant Protein (cat. No. PX-P4121) at 0.5µg/mL (100µL/well) can bind Pertuzumab Biosimilar - Anti-ERBB2, EGFR2, CD340 mAb (cat. No. PX-TA1058) in indirect ELISA with Goat Anti-Human IgG secondary antibody coupled with HRP measured by OD450 giving an EC50 at 9.566M.
Pertuzumab Biosimilar - Anti-ERBB2, EGFR2, CD340 mAb, on SDS-PAGE under reducing and non-reducing condition. The gel was stained overnight with Coomassie Blue. The purity of the antibody is greater than 95%.
Publications
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